10 Crypto DeSci that Have the Potential to Rise in 2026

Jakarta, Pintu News – The Decentralized Science (DeSci) movement is increasingly in the spotlight in the crypto world as it offers a new model of research funding, open scientific collaboration, and more transparent distribution of research results.

With a growing market capitalization and the support of the academic community and blockchain developers, DeSci tokens are predicted to be one of the strong sectors by 2026. Here’s a list of 10 DeSci cryptos that show potential based on their capitalization, utility, and development ecosystem!

1. OriginTrail (TRAC)

OriginTrail (TRAC) is a Decentralized Knowledge Graph (DKG) protocol that enables scientific, supply chain, and AI data verification. TRAC is one of the largest DeSci assets with a market valuation of around $248.8 million. The system is used in academic research, AI data labeling, and scientific dataset verification.

Within the DeSci ecosystem, OriginTrail provides a foundation of verified data that is essential for open research. TRAC is also supported by a number of European institutions and has received funding from the Horizon 2020 EU Research Program.

2. Bio Protocol (BIO)

Bio Protocol (BIO) is a DeSci token that focuses on publicly funding biotechnology research. With a market capitalization of around $104.7 million, BIO is one of the most actively traded DeSci tokens.

The protocol aims to create a mechanism for funding medical research without bureaucracy, allowing the global community to support scientific experiments through tokenization. BIO also attracted attention for being one of the top gainers in the DeSci category according to CoinGecko.

3. ResearchCoin (RSC)

ResearchCoin (RSC) is used by the ResearchHub platform, a scientific research repository backed by some of the biggest names in science. The market capitalization of RSC is around $28.2 million.

This protocol incentivizes researchers to upload, review, and contribute to scientific publications. With a token reward model, ResearchHub seeks to increase the speed of sharing scientific knowledge globally.

4. HairDAO (HAIR)

HairDAO (HAIR) is a unique DeSci project focused on developing a genetic research-based baldness therapy. The HAIR token has a market capitalization of approximately $22.5 million.

The DAO model allows participants to fund scientific research into hair follicles and tissue rejuvenation. HairDAO has already funded some initial experiments in independent labs and is one of the most visible examples of crypto-based medical collaboration.

Read also: 7 Crypto Neobanks with the Potential to Shine in 2026

5. The Innovation Game (TIG)

TIG is the token of a project that utilizes blockchain to encourage scientific innovation competition through a challenge-based science model. TIG’s market capitalization stands at $18.8 million.

Through this platform, researchers can complete certain scientific challenges and receive token rewards. The gamification structure enables research collaboration to run faster and more efficiently.

6. AxonDAO Governance Token (AXGT)

AXGT is used in AxonDAO, a DeSci project that supports the development of neurology research and health technologies. Its market capitalization stands at $14 million.

AxonDAO actively funds neuroscience, biomarker, and health AI research. AXGT tokens provide voting rights on research proposals funded by the community.

7. VitaDAO (VITA)

VitaDAO is one of the most well-known scientific DAOs that focus on longevity science or anti-aging research. VITA’s market capitalization is around $13 million.

The project has raised over $4 million in funding for biological aging research, including collaborations with several universities and biotech labs. VITA is often considered a DeSci pioneer due to its ongoing real funding activities.

Also read: 10 Crypto Cross-Chains that Have the Potential to Rise in 2026

8. Galeon (GALEON)

Galeon (GALEON) is a decentralized medical data infrastructure that facilitates AI medical diagnosis. Its market capitalization stands at $8.5 million.

Galeon collects encrypted medical data from various healthcare institutions and aggregates it for medical research without violating privacy. This model is considered essential for the acceleration of AI research in healthcare.

9. Bluzelle (BLZ)

Bluzelle (BLZ) is a decentralized data storage network that can be used for scientific datasets, research, and gaming. Bluzelle’s market capitalization is approximately $7.98 million.

As a Web3 data infrastructure, Bluzelle supports the security, integrity, and availability of scientific data. Its potential in DeSci lies in storing large research datasets on the blockchain.

10. Aubrai by Bio (AUBRAI)

AUBRAI is a DeSci project that focuses on biomedical research and community-based drug development. AUBRAI’s capitalization is around $6.96 million.

Through the DAO model, the community can choose which medical research to fund and oversee the direction of the research. The token is gaining recognition after being included in the mid-cap DeSci token list.

Conclusion

The DeSci sector offers great opportunities for the simultaneous development of scientific research and the crypto ecosystem. The above ten tokens show positive dynamics in terms of capitalization, community, and ecosystem activity throughout 2024-2025. However, risks remain high given that most projects are still at an early stage. Investors need to understand the utility of the token as well as its research roadmap before making a decision.

FAQ

What is DeSci in the cryptocurrency world?

DeSci is a decentralized scientific research movement that uses blockchain to fund research, store data, and openly distribute study results.

Why is Bio Protocol (BIO) a popular DeSci token?

BIO has a large capitalization, stable volume, and a focus on funding biotech research, making it one of the leaders of the DeSci category.

Is the DeSci project already in real use?

Some projects like VitaDAO and HairDAO are already funding real experiments in biotech and medical research labs.

What are the biggest risks of investing in DeSci tokens?

Risks include the uncertainty of research developments, price volatility, and regulatory challenges to medical and biotech data.

How to select potential DeSci tokens?

Important factors include market capitalization, community activity, research progress, and support from scientific or biotech institutions.

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*Disclaimer

This content aims to enrich readers’ information. Pintu collects this information from various relevant sources and is not influenced by outside parties. Note that an asset’s past performance does not determine its projected future performance. Crypto trading activities have high risk and volatility, always do your own research and use cold cash before investing. All activities of buying and selling bitcoin and other crypto asset investments are the responsibility of the reader.

Reference:

• Coingecko